What to expect after you get the COVID-19 shot Brazos County Health Authority Dr. Seth Sullivan says if you get sick after the shot, it’s OK. Author: Elisabeth Tharp Updated: 6:30 PM CDT March 31, 2021 BRAZOS COUNTY, Texas — Dr. Seth Sullivan, Brazos County Health Authority, said some people may experience different symptoms after they receive the shot. Some symptoms may include but are not limited to, itching, fever, or soreness in your arm. According to Dr. Sullivan, that’s all normal. Dr. Sullivan said the range of symptoms that can occur after getting the shot should only last 24 to 36 hours. If you are in pain or discomfort, Dr. Sullivan said you can take Ibuprofen, Motrin, or Tylenol.