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Experts: Prioritize COVID-19 vaccine for those with high exposure to PFAS manmade chemicals


Experts: Prioritize COVID-19 vaccine for those with high exposure to PFAS chemicals
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Experts say that people who have high exposure to PFAS chemicals found in food packaging and cleaning products, among other sources should be prioritized for the COVID-19 vaccine. File Photo by Gary I Rothstein /UPI | License Photo
Dec. 17 (UPI) People with higher levels of toxic, manmade chemicals in their bloodstream should be given priority for a COVID-19 vaccine, scientists who represent the Environmental Working Group said Thursday.
This is because these toxic per- and polyfluoroalkyl chemicals, or PFAS, which are found in many household cleaning products, pesticides and food packaging, appear to adversely affect the human immune system s ability to fight infectious diseases, the scientists said. ....

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Epoxide Hydrolase, a Fat New Target for Alzheimer's Therapy?


15 Dec 2020
Can making ephemeral anti-inflammatory fatty acids stick around a little longer protect people against Alzheimer’s disease? It just might, according to a study by Hui Zheng and colleagues at the Baylor College of Medicine, Houston, published December 9 in Science Translational Medicine.
In AD brain and 5xFAD mice, epoxide hydrolase is up and its anti-inflammatory products are down.
Astrocytes express this lipid metabolism enzyme.
In mice, inhibiting it restored epoxy fatty acids and a chain of consequences at molecular, synaptic, and behavioral levels of investigation.
These so-called epoxy fatty acids, or EpFAs, protect neurons; alas, epoxide hydrolases quickly break them down. The scientists found more epoxide hydrolase in brain tissue from people with AD and 5xFAD mice than in controls, corresponding to fewer epoxy fatty acids in the mice. Long-term treatment with an inhibitor curbed the hydrolase and boosted EpFA concentration in the mice’s ....

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2020 Analytics of the Microbiome Landscape: Publication Analytics (2011-2019), Grants Analytics (2011-2019), Clinical Trial Analytics (2015-2020), Startup Activity (2015-2020)


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The report gives insights into the transformational microbiome landscape. It is a rigorous assessment of the industry trends supported by detailed segmentation across publications, grants, clinical trials, and startup funding activity.
The dataset behind the report is based on real world evidence that will drive actionable business insights. Follow trends over the years captured across publications, grants, clinical trials, and startup funding activity to power data driven marketing campaigns to fund raising to investor pitches, and business/corporate development activities. Tap into premium data sources that leverage NLP and relational search paradigm to uncover relevant data points, all in one package. ....

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USA Drone Port, UK-CARES and Kentucky Homeplace Partner to Bring PPE to Rural Kentuckians


Video by Research Communications
LEXINGTON, Ky. (Dec. 15, 2020) The COVID-19 pandemic introduced many new actions to our daily lives wearing masks, washing hands more frequently, and watching our distance from others. Add these health behaviors on top of already existing challenges like isolation, transportation and access to health care, and creative solutions are more necessary than ever. 
That’s why the UK Center for Appalachian Research in Environmental Sciences (UK-CARES) with the UK Center of Excellence in Rural Health, Kentucky Homeplace and the USA Drone Port joined forces this fall to explore the use of drones to deliver Personal Protective Equipment (PPE) to people in Appalachian Kentucky.  ....

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