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Scientists Identify Genetic Pathway that Suppresses Lou Gehrig's Disease


Date Time
Scientists Identify Genetic Pathway that Suppresses Lou Gehrig’s Disease
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS).
Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and exchange protein directly activated by cyclic AMP 1 (EPAC1) that sustains the nucleocytoplasmic RAN gradient and thereby suppresses NCT dysfunction by the C9ORF72-derived poly (glycine-arginine) protein. ....

South Korea , Lou Gehrig , Jongbo Lee , Department Of Biological Sciences , National Research Foundation Of Korea , Korea Health Technology , Suh Kyungbae Foundation , Korean Ministry Of Health , Professor Chunghun Lim , Biological Sciences , National Research Foundation , Korea Health Technology Rd Project , Korean Ministry , Ju Min Park , Ji Hyung Kim , Ministry Of Health , Amyotrophic Lateral Sclerosis , Health Technology , Cell Nucleus , தெற்கு கொரியா , லூ கேஹ்ரிக் , துறை ஆஃப் உயிரியல் அறிவியல் , தேசிய ஆராய்ச்சி அடித்தளம் ஆஃப் கொரியா , கொரியா ஆரோக்கியம் தொழில்நுட்பம் , கொரியன் அமைச்சகம் ஆஃப் ஆரோக்கியம் , உயிரியல் அறிவியல் ,

New study investigates how life on land recovered after "The Great Dying"


Date Time
New study investigates how life on land recovered after “The Great Dying”
Lystrosaurus: After the mass extinction, the ecosystem was unusual, with hugely common examples of the dicynodont Lystrosaurus [2,3], sometimes comprising 90% of the assemblage. Some smaller reptiles also survived, and these were preyed on by rare, water-dwelling proterosuchians [8].
Xiaochong Guo
Over the course of Earth’s history, several mass extinction events have destroyed ecosystems, including one that famously wiped out the dinosaurs. But none were as devastating as “The Great Dying,” which took place 252 million years ago during the end of the Permian period.
A new study, published today in Proceedings of the Royal Society B, shows in detail how life recovered in comparison to two smaller extinction events. ....

United States , Mike Benton , Xiaochong Guo , Peter Roopnarine , Yuangeng Huang , Zhong Qiang Chen , China University Of Geosciences , Proceedings Of The Royal Society , Chinese Academy Of Sciences , California Academy Of Sciences , Academy Curator Of Geology , University Of Bristol , University Of Geosciences Wuhan , Missouri University Of Science , Great Dying , China University , California Academy , Missouri University , Chinese Academy , Academy Curator , Professor Mike Benton , Professor Zhong Qiang Chen , North China , University Of Science And Technology , Mass Extinction , Royal Society ,

Arts and Culture Queen Mary launches its Conversations Week


Queen Mary University of London
In 2020, Arts and Culture at Queen Mary University of London invited UK-based artists to converse with academics from across the university, using its Higher Education Innovation Fund. A dentist spoke to a sculptor. A mathematician to a choreographer. A dramatist to an opera singer.
While an unforeseen pandemic limited human contact for many of us, these artists and academics found ways to talk. They held conversations about climate change, mental health, housework, racism, childcare, justice, wellbeing. They exchanged knowledge. Expertise. Then the artists set to work.
The results are original artworks and creative responses that could not have happened without conversations between academics and artists. They remind us of the power of art and the impact of connecting deep thinkers across fields. Watch the video on Vimeo. ....

City Of , United Kingdom , Lois Weaver , Queen Mary , Magda Osman , Patrick Healey , Barbara Taylor , Higher Education Innovation Fund , Raphael Samuel History Centre , Queen Mary University Of London , Queen Mary University , United Kingdom Based , Higher Education Innovation , Queen Mary Conversations Week , Mary Conversations , Human Interaction Patrick Healey , History Barbara Taylor , Experimental Cognitive Psychology Magda Osman , Contemporary Performance , Queen Mary Conversations , Aoife Monks , Performance Studies , Academic Lead , Climate Change , Mental Health , Child Care ,

EPFL algorithm in world's most popular deep learning software


Artificial Intelligence technology © 2021 4X-image
PyTorch is used for countless AI applications ranging from Tesla’s Autopilot to Facebook’s translation software and its latest version, just launched, features an EPFL communication-efficient training algorithm that even helps the planet.
Deep learning is part of a broader family of machine learning methods, based on artificial neural networks, and has allowed us to develop everything from voice and image recognition tools, enhance drug discovery and toxicology, and improve financial fraud detection.
As the applications of machine learning become bigger, more complex and increasingly ubiquitous in our modern, digital age, neural networks have grown tremendously in size, consisting of trillions of connections. To train these models faster, researchers typically distribute the training effort over many computers or Graphics Processing Units yet, just like humans that collaborate to solve a task, collaborating comput ....

Thijs Vogels , Praneeth Karimireddy , Martin Jaggi , Communications Sciences , School Of Computer , Optimization Laboratory , Artificial Intelligence , Graphics Processing Units , Machine Learning , Sai Praneeth Karimireddy , Climate Change , Deep Learning , மார்டின் ஜாகி , தகவல்தொடர்புகள் அறிவியல் , பள்ளி ஆஃப் கணினி , தேர்வுமுறை ஆய்வகம் , செயற்கை உளவுத்துறை , கிராபிக்ஸ் ப்ரோஸெஸிஂக் அலகுகள் , இயந்திரம் கற்றல் , காலநிலை மாற்றம் , ஆழமான கற்றல் ,