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Simple blood test could replace surgery for some brain tumour patients

Date Time
Simple blood test could replace surgery for some brain tumour patients
A research breakthrough shows that a simple blood test could reduce, or in some cases replace, the need for intrusive surgery when determining the best course of treatment for patients with a specific type of brain tumour.
Researchers at the Brain Tumour Research Centre of Excellence at the University of Plymouth have discovered a biomarker which helps to distinguish whether meningioma – the most common form of adult primary brain tumour – is grade I or grade II.
The grading is significant because lower grade tumours can sometimes remain dormant for long periods, not requiring high risk surgery or harsh treatments such as radiotherapy and chemotherapy. Tumours classified as grade II can progress to become cancerous and more aggressive treatment may be needed in order to try to control their spread. ....

United Kingdom , Oliver Hanemann , Hugh Adams , Plymouth Centre Of Excellence , International Journal Of Molecular Sciences , Brain Tumour Research , Brain Tumour Research Centres Of Excellence , Brain Tumour Research Centre Of Excellence , University Of Plymouth , Brain Tumour Research Centre , Professor Oliver Hanemann , International Journal , Brain Tumour Research Centres , Tumour Research Centre , Tumour Research , Liquid Biopsy , ஒன்றுபட்டது கிஂக்டம் , ஆலிவர் ஹேன்மேன் , ஹக் ஆடம்ஸ் , ப்லிமத் மையம் ஆஃப் சிறப்பானது , சர்வதேச இதழ் ஆஃப் மூலக்கூறு அறிவியல் , மூளை கட்டி ஆராய்ச்சி , மூளை கட்டி ஆராய்ச்சி மையங்கள் ஆஃப் சிறப்பானது , மூளை கட்டி ஆராய்ச்சி மையம் ஆஃப் சிறப்பானது , பல்கலைக்கழகம் ஆஃப் ப்லிமத் , மூளை கட்டி ஆராய்ச்சி மையம் ,

Scientists develop rapid test for diagnosis of rare set of genetic conditions

Queen Mary University of London
Telomeropathies are caused by premature shortening of the tips of chromosomes, the DNA molecules which contain our genetic information.
They can result in a range of symptoms, including bone marrow failure, pulmonary fibrosis, cancer and liver disease in adults and children. There are currently about 1,000 people living with telomeropathies in the UK, many of which are undetected.
Now, researchers have developed a rapid laboratory test for diagnosing patients showing the many different types of symptoms that can arise from telomeropathies.
The technique, called high-throughput single telomere length analysis (HT-STELA), is a DNA-based blood test that provides high-resolution information. The researchers say it can be applied to a broader range of samples than existing tests, including fresh or frozen blood samples as well as DNA. ....

United Kingdom , Markj Ponsford , Alicia Ellison , Kevin Norris , Amandaj Walne , Inderjeet Dokal , Jenna Alnajar , Juliaw Grimstead , Professor Duncan Baird At Cardiff University , Cancer Research United Kingdom , Cardiff University , Wales Cancer Research Centre , Research Council , Professor Tom Vulliamy , Queen Mary , Blizard Institute , Professor Duncan Baird , Medical Research Council , Welsh Clinical Academic Training , Kez Cleal , Tom Vulliamy , Queen Mary University Of London , Medical Research , Life Expectancy , Cancer Research , ஒன்றுபட்டது கிஂக்டம் ,

Stimulating Immune System to Fight Cancer

Max Planck scientists from Dortmund find immunoregulatory substances with newly developed test system
Cancer cells have evolved mechanisms to escape the body’s immune defense. Agents that prevent immune escape are attractive targets for the development of new cancer therapies. A group of scientists led by Herbert Waldmann and Slava Ziegler at the Max Planck Institute of Molecular Physiology in Dortmund has now developed a new cell-based test system to identify immunoregulatory modulators. Screening a library of over 150,000 substances revealed several potent substances with unprecedented structure.
384-well plate for the detection of potential Inhibitors.
© MPI of Molecular Physiology
Our immune system is very successful when it comes to warding off viruses and bacteria. It also recognizes cancer cells as potential enemies and fights them. However, cancer cells have developed strategies to evade surveillance by the immune system and to preven ....

Slava Ziegler , Herbert Waldmann , Max Planck , Elisabeth Hennes , Max Planck Institute , Molecular Physiology , Different Mechanisms , Max Planck Society , Immune Response , Clinical Trials , ஹெர்பர்ட் வால்ட்மேன் , மூலக்கூறு உடலியல் , நோய் எதிர்ப்பு சக்தி பதில் , மருத்துவ சோதனைகள் ,

Researchers reveal extent to which rivers across country are losing flow to aquifers

Researchers reveal the extent to which rivers across the country are losing flow to aquifers
By Harrison Tasoff
Leaky rivers are more widespread than scientists had thought.
Water is an ephemeral thing. It can emerge from an isolated spring, as if by magic, to birth a babbling brook. It can also course through a mighty river, seeping into the soil until all that remains downstream is a shady arroyo, the nearby trees offering the only hint of where the water has gone.
The interplay between surface water and groundwater is often overlooked by those who use this vital resource due to the difficulty of studying it. Assistant professors Scott Jasechko and Debra Perrone, of UC Santa Barbara, and their colleagues leveraged their enormous database of groundwater measurements to investigate the interaction between these related resources. Their results, published in Nature, indicate that many more rivers across the United States may be leaking water into the ground than pr ....

United States , Santa Ynez River , Scott Jasechko , Santa Barbara , Debra Perrone , Photo Credit , World War , Santa Ynez , Uc Santa Barbara , Eth Zurich , Ground Water , ஒன்றுபட்டது மாநிலங்களில் , சாந்தா ய்னேஜ் நதி , சாந்தா பார்பரா , டெப்ரா பெரோன் , புகைப்படம் கடன் , உலகம் போர் , சாந்தா ய்னேஜ் , அக் சாந்தா பார்பரா , எத் ஸுரி , தரையில் தண்ணீர் ,

New clubroot strains show genetic resistance isn't enough to protect canola, say researchers

Date Time
New clubroot strains show genetic resistance isn’t enough to protect canola, say researchers
Nine new strains of clubroot a disease that can kill canola crops have been discovered in Western Canadian fields by University of Alberta researchers.
While that’s not good news for producers, the discovery shows how important it is to build a multi-pronged strategy for protecting their crops, not relying solely on canola plants bred to resist the disease, said lead researcher Keisha Hollman.
The discovery of the new pathogens in canola fields tested across Alberta, Saskatchewan and Manitoba in 2017 and 2018 means resistance breakdown first discovered in 2013 is growing. ....

Keisha Hollman , University Of Alberta , Life Environmental Sciences , Strategic Research , Development Program Of Alberta Agriculture , Western Canadian , Canadian Journal , Plant Pathology , Agricultural Pests Act , Alberta Canola , Manitoba Canola Growers , Development Program , Alberta Agriculture , கேஷா ஹோல்மேன் , பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டா , வாழ்க்கை சுற்றுச்சூழல் அறிவியல் , மூலோபாய ஆராய்ச்சி , மேற்கு கனடியன் , கனடியன் இதழ் , ஆலை நோயியல் , ஆல்பர்ட்டா கனோலா , ம்யாநிடோப கனோலா விவசாயிகள் , வளர்ச்சி ப்ரோக்ர்யாம் , நீண்ட ஆயுள் ,