Stay updated with breaking news from Ace2. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.
Researchers at the University of California, San Diego, have demonstrated the potential of using green algae to make recombinant viral proteins that could be used in large scale assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19).
Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2 Among the hundred million or so cases of coronavirus disease 2019 (COVID-19) that have occurred since the pandemic began, pregnant women have been a conspicuous risk group. However, the exact nature of the risk they and their fetuses face, and the mechanism by which it operates, is far from clear. A new preprint research paper posted to the medRxiv* server throws some light on this area by revealing the presence of significant inflammation at the maternal-fetal interface. Study: SARS-CoV-2 infecti...
.jpg)
A team of scientists from the United States has recently revealed that about 25% of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop renal complications and that the viral spike protein can be detected in the urine samples of these patients. The study is currently available on the medRxiv* preprint server.
.jpg)
Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19). In a study using two human cell lines, a combination of the clinical drugs triclabendazole and emetine effectively suppressed expression of the host cell receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (C...