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Startup develops yeast-based test to detect the presence of SARS-CoV-2 in saliva Incubated at the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, and supported by São Paulo Research Foundation- FAPESP's Innovative Research in Small Business Program (PIPE), BIOinFOOD is a startup that is developing a rapid COVID-19 diagnostic test based on a patent application filed by students at UNICAMP's Genomics and Bioenergy Laboratory. The test is based on a biosensor consisting of a genetically modified brewer's yeast (Saccharomyces cerevisiae), which changes color if human ACE2 re...

India's Covaxin Neutralizes UK Variant of Covid by Hannah Joy on  January 28, 2021 at 12:39 PM Covaxin can now neutralize UK variants of SARS-CoV-2 effectively by reducing the possibility of mutant virus escape. Covaxin is developed Bharat Biotech in Hyderabad, India. According to the research paper carried by bioRxiv, the preprint server for biology, the study has dispelled the uncertainty of possible neutralization escape. A group of researchers from Indian Council of Medical Research(ICMR), National Institute of Virology, Pune and Bharat Biotech performed the plaque redu...

Now, in new research posted to the preprint server bioRxiv*, scientists use an experimental structure of the Spike RBD domain co-crystallized with part of the ACE2 receptor and several in silico methods to analyze the possible impacts of three amino acid replacements (Spike K417N, E484K, N501Y) concerning ACE2 binding.

Using more than 100,000 virus genome sequences uploaded in the GISAID database, researchers found around 9,000 mutations in the virus spike protein RBD.

Researchers studying the effect of convalescent sera and monoclonal antibodies from recovered patients found the UK and South African SARS-CoV-2 variants are more resistant to neutralization compared to the wild-type virus.