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A recent study by US researchers shows how the 501Y.V2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by several mutations, is able to escape neutralization by present first-wave anti-SARS-CoV-2 antibodies and potentially re-infect COVID-19 convalescent individuals.
Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans? The potentially deadly coronavirus disease 2019 (COVID-19) that has swept the world over the last 12 months has not affected animals with corresponding severity. In order to understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new preprint appearing on the bioRxiv* server indicates that this may not be a faithful model of human letha...
There have been significant efforts worldwide to combat COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One prominent strategy has been to develop vaccines against the virus. Numerous vaccine candidates are under development, and a handful have now been approved for use by several countries.
A new potential therapy for COVID-19 developed by researchers at Rush University Medical Center has shown success in preventing the disease's symptoms in mice.
White-tailed deer susceptible to SARS-CoV-2 infection, study finds A team of scientists from the United States has recently demonstrated that white-tailed deer are highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, the infected animals are capable of transmitting the virus to their non-infected counterparts via indirect contact. The study is currently available on the Background Although there is uncertainty about the exact origin of SARS-CoV-2, a pathogen spillover from animals to humans is likely responsible for the emergence of coronavi...