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To Speed Vaccination, Some Call for Delaying Second Shots Stretching the time between the first and second doses would greatly accelerate the rate at which people get at least partial protection. But some experts fear it could also lead to new variants. People without appointments waited outside a mass Covid vaccination site in Hagerstown, Md., this week.Credit...Chip Somodevilla/Getty Images April 9, 2021Updated 6:16 p.m. ET The prospect of a fourth wave of the coronavirus, with new cases climbing sharply in the Upper Midwest, has reignited a debate among vaccine experts over how long to wai...

Date Time How Childhood Infections Could Shape Pandemics A child’s first influenza infection shapes their immunity to future airborne flu viruses—including emerging pandemic strains. But not all flu strains spur the same initial immune defense, according to new findings published today by University of Pittsburgh School of Medicine virologists in the journal PLOS Pathogens. “These results are relevant right now to the COVID-19 pandemic,” said senior author Seema Lakdawala, Ph.D., assistant professor of microbiology and molecular genetics at Pitt. “They may explain age-based distribu...

 E-Mail Credit: UPMC PITTSBURGH, Feb. 18, 2021 - A child's first influenza infection shapes their immunity to future airborne flu viruses--including emerging pandemic strains. But not all flu strains spur the same initial immune defense, according to new findings published today by University of Pittsburgh School of Medicine virologists in the journal PLOS Pathogens. "These results are relevant right now to the COVID-19 pandemic," said senior author Seema Lakdawala, Ph.D., assistant professor of microbiology and molecular genetics at Pitt. "They may explain age-based distributions of SARS-...

Over the course of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, the clinical, scientific, and public health communities have had to respond to new viral genetic variants. Each one has triggered a flurry of media attention, a range of reactions from the scientific community, and calls from governments to either “stay calm” or pursue immediate countermeasures. While many scientists were initially skeptical about the significance of the D614G alteration, the emergence of the new “UK variant”—lineage B.1.1.7—has raised widespread concern. Understanding wh...