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July 6, 2021 By Deborah Borfitz July 6, 2021 | A trio of universities are putting their heads together to engineer a wirelessly controlled bioelectronic implant intended to help soldiers adapt to new time zones or drastic changes in their work schedules by releasing peptide-based therapies to harmonize their central and peripheral circadian clocks. The solicitation came from the Defense Advanced Research Projects Agency (DARPA) and the timeline is ambitious, with a first-in-human safety study expected to begin by 2025, according to Jonathan Rivnay, principal investigator of the p...

Nanotechnology Now Our NanoNews Digest Sponsors Home > Press > Implantable 'living pharmacy' could control body's sleep/wake cycles: Project receives DARPA contract worth up to $33 million over 4 1/2 years In this artistic illustration, a user with an NTRAIN implant and its accompanying external hub works in the field. The user inputs a desired time shift (due to shift work or travel across time zones). Based on cues from the body’s physiology, the external hub detects the user’s circadian rhythm, and triggers the implant to produce precisely-dosed peptide therapies. Abstract: •Device will...