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Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

New genetic factors that affect the plasma apolipoprotein E levels. ....

United States , Molecular Psychiatry Journal , Ginkgo Evaluation , European Americans , Lzheimer 39s Disease , Central Nervous System , Ognitive Function , Nervous System ,

Gene variant protects against Alzheimer's and Parkinson's diseases

About one in every five people carries a version of a gene that, although largely unsung, appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their colleagues have learned. ....

United States , Aditya Ambati , Michael Greicius , Yann Le Guen , Iqbal Farrukh , Vincent Damotte , Jean Charles Lambert , Guo Luo , Emmanuel Mignot , Danielle Ellis , European Union , Proceedings Of The National Academy Sciences , Michaelj Fox Foundation , Japan Agency For Medical Research , Swedish Research Council , University Of Lille , Asad Jamal Fund , Stanford University , Feinstein Center , Alzheimer Association , Swedish State Support For Clinical Research , European Research Council , National Institutes Of Health , Stanford Medicine , National Academy , Craig Reynolds Professor ,

Study finds that germline-encoded specificities cannot always predict the trajectory of B-cell responses

Researchers used computational simulations and experiments to investigate how genetic variations encoded in the germline impact B-cell responses. ....

Kateryna Kon Shutterstock , B Cell ,

The outcome of invasive S. pyogenes infection is regulated by an interplay between human STING genotype and bacterial NADase activity

The interplay between human STING genotype and bacterial NADase activity. ....

Kateryna Kon Shutterstock , Nature Communications ,

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers identify an association between the C-reactive protein gene variant rs1205 and COVID-19 severity. ....

United States , World Health Organization , Genetic Variant , Strong Heart Study , Strong Heart Family , Image Credit , American Indian , Alaskan Native , American Indian Tribal , Strong Heart Family Study , American Indians , South Dakotas , Coronavirus Disease Covid 19 , Cardiovascular Disease , C Reactive Protein , Immune System , Infectious Diseases , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,