Your Gut Senses Difference Between Real Sugar and Artificial Sweetener
A section of mouse intestines shows in green the relatively scarce neuropod cells in the epithelium that are responsible for communicating conditions
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A section of mouse intestines shows in green the relatively scarce neuropod cells in the epithelium that are responsible for communicating conditions
DURHAM, N.C. – Your taste buds may or may not be able to tell real sugar from a sugar substitute like Splenda, but there are cells in your intestines that can and do distinguish between the two sweet solutions. And they can communicate the difference to your brain in milliseconds. Not long after the sweet taste receptor was identified in the mouths of mice 20 years ago, scientists attempted to knock those taste buds out. But they were surprised to find that mice could still somehow discern and prefer natural sugar to artificial sweetener, even without a sense of taste.