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A section of mouse intestines shows in green the relatively scarce neuropod cells in the epithelium that are responsible for communicating conditions

DURHAM, N.C. – Your taste buds may or may not be able to tell real sugar from a sugar substitute like Splenda, but there are cells in your intestines that can and do distinguish between the two sweet solutions. And they can communicate the difference to your brain in milliseconds. Not long after the sweet taste receptor was identified in the mouths of mice 20 years ago, scientists attempted to knock those taste buds out. But they were surprised to find that mice could still somehow discern and prefer natural sugar to artificial sweetener, even without a sense of taste.

Unsplash Researchers have figured out how to block the molecular signals that cause scars to form, at least in mice. The breakthrough is found in a 20-year-old drug used to treat macular degeneration. Today on Wellness Wednesday on All Sides with Ann Fisher: healing without scarring and the hurdles ahead. Guests: Dr. Arielle Sheftall, a Principal Investigator at the Abigail Wexner Research Institute at Nationwide Children’s Hospital in the Center for Suicide Prevention and Research and an Assistant Professor of Pediatrics at the Ohio State University Medical Center Dr. Michael Longaker, D...