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Penn State University: Repurposing FDA-approved drugs may help combat COVID-19

Several FDA-approved drugs including for type 2 diabetes, hepatitis C and HIV significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. Specifically ....

Evaj Pell , Katsuhiko Murakami , Joyce Jose , Anoop Narayanan , Manju Narwal , Communications Biology , Laboratory For Advanced Biological Research At Penn , Penn State , Advanced Biological Research ,

Young filmmakers should focus on unsung heroes of freedom struggle, says MoS L Murugan

Union Minister of State for Information and Broadcasting Dr L Murugan on Sunday attended the SHE Short Film Festival Awards ceremony based on the theme of women s safety and said that young filmmakers should focus on unsung heroes of the freedom struggle. ....

Bharat Mata , Karuvariyin Kanavukal , Anoop Narayanan , Film Facilitation Office , Union Minister , Broadcasting Drl Murugan , Film Festival Awards , She Short Film Festival , Central Government , Sarath Sunder , Ews India ,

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy


Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy
What if the COVID-19 virus could be used against itself? Researchers at Penn State have designed a proof-of-concept therapeutic that may be able to do just that. The team designed a synthetic defective SARS-CoV-2 virus that is innocuous but interferes with the real virus s growth, potentially causing the extinction of both the disease-causing virus and the synthetic virus.
In our experiments, we show that the wild-type [disease-causing] SARS-CoV-2 virus actually enables the replication and spread of our synthetic virus, thereby effectively promoting its own decline. A version of this synthetic construct could be used as a self-promoting antiviral therapy for COVID-19. ....

Marco Archetti , Joyce Jose , Anoop Narayanan , Emily Henderson , Penn State , Associate Professor , Shun Yao , Sydney Majowicz , மகிழ்ச்சி ஜோசே , அனூப் நாராயணன் , எமிலி ஹென்டர்சன் , பென் நிலை , இணை ப்ரொஃபெஸர் ,