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Gene-Wei Li and Michael Birnbaum named Pew Innovation Fund investigators

MIT professors Gene-Wei Li and Michael Birnbaum are among the 12 researchers named 2023 Innovation Fund investigators by The Pew Charitable Trusts.

Pennsylvania-state-university , Pennsylvania , United-states , Philadelphia , America , Katsuhiko-murakami , Donna-frisby-greenwood , Dan-littman , Michael-birnbaum , Wei-li , Career-development-professor , Department-of-biology

Pew funds 6 teams to advance cutting-edge bio

<p>The Pew Charitable Trusts announced today the six pairs of researchers who will make up its 2023 class of Innovation Fund investigators. These 12 acclaimed scientists&mdash;all alumni or advisors of Pew&rsquo;s biomedical programs in the United States and Latin America&mdash;will partner on interdisciplinary research projects exploring key questions in human biology and disease</p>

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Pennsylvania-state-university , Pennsylvania , United-states , Philadelphia , America , American , Kathrynw-davis , Donna-frisby-greenwood , Wei-li , Michael-birnbaum , Danr-littman , Luisg-brieba

Process for Covid Replication Visualized

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Essential process for SARS-CoV-2 viral replication visualized

During the replication of the SARS-CoV-2 virus, a long string of connected proteins is cleaved apart into individual proteins. This process is interrupted by an FDA-approved drug to treat COVID-19; however, the mechanistic details of this cleavage process are still unclear. Now, a team led by researchers at Penn State have produced the most detailed images to date of this process.

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Penn State University: Repurposing FDA-approved drugs may help combat COVID-19

Several FDA-approved drugs — including for type 2 diabetes, hepatitis C and HIV — significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. Specifically

Evaj-pell , Katsuhiko-murakami , Joyce-jose , Anoop-narayanan , Manju-narwal , Communications-biology , Laboratory-for-advanced-biological-research-at-penn , Penn-state , Advanced-biological-research ,

Repurposing FDA-approved drugs may help combat COVID-19

Several FDA-approved drugs — including for type 2 diabetes, hepatitis C and HIV — significantly reduce the ability of the Delta variant of SARS-CoV-2 to

California , United-states , San-diego , Evaj-pell , Katsuhiko-murakami , Shaya-toner , Anoop-narayanan , Carlo-ballatore , Manju-narwal , Carmine-varricchio , Andrea-brancale , Joyce-jose

Repurposing FDA-approved drugs may help combat Covid

Several FDA-approved drugs -- including for type 2 diabetes, hepatitis C and HIV -- significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, finds new research.Specifically, the team found that these ...

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Repurposing FDA-approved drugs may help combat Covid

Repurposing FDA-approved drugs may help combat Covid
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Solving ancient problem of nucleic acid synthesis helps to design new antiviral drugs


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An international team of scientists from the University of Turku, Finland and PennState University, USA have solved a long-standing mystery of how living organisms distinguish RNA and DNA building blocks during gene expression paving the way for the design of new antiviral drugs. The new insights were published in the journal
Nature Communications.
All cellular organisms use two types of nucleic acids, RNA and DNA to store, propagate and utilize their genetic information. The synthesis of DNA is carried out by enzymes called DNA polymerases and is needed to accurately transfer the genetic information from generation to generation. Synthesis of RNA is carried out by enzymes called RNA polymerases and is needed to utilize the genetic information to ultimately produce proteins that in turn fulfil most structural and catalytic functions in all modern-day living organisms.

Finland , United-states , Katsuhiko-murakami , Georgi-belogurov , Nature-communications , National-institute-of-health-united-states , Penn-state-university , Development-of-more-effective-antiviral-drugs , Academy-of-finland , University-of-turku , Sigrid-juselius-foundation-finland , Senior-researcher-georgi