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Novel hydrogel slowly releases RNA nanovaccines to shrink tumors

Novel hydrogel slowly releases RNA nanovaccines to shrink tumors
Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer. Now, researchers reporting in ACS
Nano Letters have developed a hydrogel that, when injected into mice with melanoma, slowly released RNA nanovaccines that shrank tumors and kept them from metastasizing.
Cancer immunotherapy vaccines work similarly to mRNA vaccines for COVID-19, except they activate the immune system to attack tumors instead of a virus. These vaccines contain mRNA that encodes proteins made specifically by tumor cells. When the mRNA enters antigen-presenting cells, they begin making the tumor protein and displaying it on their surfaces, triggering other immune cells to seek and destroy tumors that also make this protein. However, mRNA is an unstable molecule that is quic ....

Chai Wang , Emily Henderson , Nano Letters , Immune System , ஹாய் வாங் , எமிலி ஹென்டர்சன் , நானோ எழுத்துக்கள் , நோயெதிர்ப்பு சிகிச்சை , நோய் எதிர்ப்பு சக்தி அமைப்பு ,

SARS-CoV-2 D614G mutation associated with lower antibody binding

The onset of the COVID-19 pandemic has brought about an international effort to uncover the biology of its causative agent, SARS-CoV-2, and to develop effective and safe antivirals to contain and treat the infection. A new study by a team of researchers in France and Sweden discusses one such study, exploring the relative immunogenicity of the three main structural proteins of the virus. ....

Liji Thomas , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Immune System , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , Spike Protein , கொரோனா வைரஸ் , நோய் எதிர்ப்பு சக்தி அமைப்பு , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , ஸ்பைக் ப்ரோடீந் ,

Agreement Speeds Access to SARS-Cov-2 Antigen Test

A partnership which will accelerate Avacta’s AffiDX™ SARS-CoV-2 lateral flow rapid antigen test to market is enabling the test to be CE marked for professional use under Mologic’s existing ISO13485 quality system. Click to read more. ....

United Kingdom , Mark Davis , Alastair Smith , Avacta Affi , Avacta Group , Abingdon Health , Global Access Diagnostics , Chief Executive Officer , ஒன்றுபட்டது கிஂக்டம் , குறி டேவிஸ் , அலெஸ்டர் ஸ்மித் , அபிங்டோன் ஆரோக்கியம் , உலகளாவிய நுழைவு பரிசோதனை , தலைமை நிர்வாகி அதிகாரி ,

Georgia nears 800,000 virus cases

ATLANTA – Georgia reported more than 2,200 new COVID-19 cases Thursday as the state closed in on 800,000 cases since the start of the pandemic, according to the Georgia Department ....

United States , Georgia Department Of Public Health , Georgia Department , Health Official , ஒன்றுபட்டது மாநிலங்களில் , ஜார்ஜியா துறை ஆஃப் பொது ஆரோக்கியம் , ஜார்ஜியா துறை , உயிர் வேதியியல் , ஆரோக்கியம் அதிகாரி ,

Labcorp Adds Antigen Test To Screen For Active COVID-19 Infection

WASHINGTON (dpa-AFX) - Laboratory Corporation of America Holdings (LH) announced the availability of a new laboratory-based antigen test that will help doctors determine if an individual is actively ....

United States , Drug Administration On , Laboratory Corp Of America Aktie , Laboratory Corporation Of America Holdings , America Holdings , Drug Administration , Co Vid , ஒன்றுபட்டது மாநிலங்களில் , ஆய்வகம் நிறுவனம் ஆஃப் அமெரிக்கா ஹோல்டிங்ஸ் , அமெரிக்கா ஹோல்டிங்ஸ் , இணை வித் ,