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Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses. ....

Andrii Vodolazhskyi Shutterstock , National Center , Nature Biomedical Engineering , Biotechnology Information , Coronavirus Disease Covid 19 , Covid 19 , N Vitro , N Vivo , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

CD1 lipidomes exhibit size-based antigen display mechanisms

Study uncovers the complexities of how CD1 molecules present a vast array of lipids to T-cells, revealing a unique, size-based antigen-display system. The findings could provide crucial insights into the intricacies of immune response and antigen presentation. ....

Crevis Shutterstock , High Throughput , T Cell ,