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Analytical and clinical evaluation of antigen-based rapid diagnostic tests against the most encountered SARS-CoV-2 variants

A recent study has assessed the sensitivity of Ag-RDTs against the most prevalent BA.5 Omicron sub-lineage. ....

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Unused Covid tests worth almost $160m could be wasted

The Health Minister says Te Whatu Ora needs to 'get on with' finding a solution. ....

New Zealand , Te Whatu , New Zealand General , New Zealanders , Chris Hipkins , Brooke Van Velden , Van Velden , Ayesha Verrall , Health New Zealand , Health Minister Dr Ayesha Verrall , Herald Te Whatu Ora , Border Orders , Whatu Ora , Health Minister , Prime Minister Chris Hipkins ,

CHOP researchers engineer stable, universal MHC-I molecules in a shorter timeframe

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on the cell surface, "presenting" them to the immune system, which is constantly scanning the body for foreign or toxic antigens. ....

University Of Pennsylvania , United States , Fox Chase Cancer Center , Michaelc Young , George Burslem , Lily Ramsey , Nikolaosg Sgourakis , Yi Sun , Claireh Woodward , Sgourakis Lab , Proceedings Of The National Academy Sciences , National Academy , Senior Author , Associate Professor , Genomic Medicine , Immune Response , Immune System ,

Multiple sclerosis: Immune cell invasion enabled by blood-brain barrier breakdown

Blood-brain barrier breakdown in multiple sclerosis leads to immune cell infiltration into the central nervous system. Antigen presentation at the barrier promotes CD8+ T cell entry, triggering focal breakdown and hindering their invasion. ....

Nemes Laszlo , Nature Communications , Cell Migration , Central Nervous System , N Vitro , Multiple Sclerosis , Nervous System , Pd L1 , T Cell ,

What is HMPV, which US doctors say is the 'most important virus you've never heard of'?

Human metapneumovirus, or HMPV, is an illness that affects the upper respiratory system, causing similar COVID-19 symptoms, such as cough, sore throat, and fever. While it can affect people of all ages, the risk is higher for children, older adults, and those with compromised immune systems ....

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