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“Life and health can never be exchanged for other benefits within the society.” With this vision, the Swedish Parliament in 1997 adopted Vision Zero, a road traffic safety project that aims to minimize serious injuries and fatalities surrounding road traffic accidents. Vision Zero revisioned the concept of road users as the ultimate responsibility bearers but rather the responsibility is shared by transportation system designers and road users.

The majority of genetic variants for psychiatric disorders have been found within non-coding genomic regions. Physical interactions of gene promoters with distant regulatory elements carrying risk alleles may explain how the latter affect gene expression. Recently, whole genome maps of long-range chromosomal contacts from human postmortem brains have been integrated with gene sequence and chromatin accessibility data to decipher disease-specific alterations in chromatin architecture. Cell culture and rodent models provide a causal link between chromatin conformation, long-range chromosomal con...