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Muna Therapeutics Raises $73 Million to Advance Neurodegenerative Disease Focus - Vimarsana News

Muna Therapeutics Raises $73 Million to Advance Neurodegenerative Disease Focus

Published: Jul 09, 2021 By Brandon May Muna Therapeutics, a private Denmark- and Belgium-based biopharmaceutical company founded in 2020, officially closed a $73 million Series A financing round. The company launches with the new funding to advance its focus on first-in-class small molecule therapies for neurodegenerative diseases. The Series A financing was led by Novo Holdings in conjunction with Sofinnova Partners, DROIA Ventures and LSP Dementia Fund. Additional investors who joined the financing round included Polaris Partners, Polaris Innovation Fund, Sanofi Ventures, V-Bio Ve...

UK budget muted on research with no Horizon Europe money - Vimarsana News

UK budget muted on research with no Horizon Europe money

Visa fine-tuning to create "radically simplified bureaucracy for high-skilled applications", with quicker processes for entrepreneurs, was a research highlight in the UK’s annual budget on Wednesday. But science groups are left perplexed by the missing billions of pounds earmarked for participation in the EU’s Horizon Europe research programme.

UK budget offers a few crumbs for research, but no Horizon Europe money - Vimarsana News

UK budget offers a few crumbs for research, but no Horizon Europe money

04 Mar 2021   |   News UK budget offers a few crumbs for research, but no Horizon Europe money There are tweaks to the talent visa, but science funding ‘notably scarce’, while there’s no mention of how the government will meet the costs of EU science participation Visa fine-tuning to create "radically simplified bureaucracy for high-skilled applications", with quicker processes for entrepreneurs, was a research highlight in the UK’s annual budget on Wednesday. But science groups are left perplexed by the missing billions of pounds earmarked for participation in the EU’s Horizon E...

Striking Microgliosis in New APP Knock-in Mice - Vimarsana News

Striking Microgliosis in New APP Knock-in Mice

06 Feb 2021 A new APP knock-in mouse has hit the scene. Researchers led by Pascal Sanchez, Denali Therapeutics, San Francisco, California, described the details in a paper posted to bioRxiv on January 20. They humanized the Aβ sequence in the mouse APP gene and knocked in three familial Alzheimer’s disease mutations: Swedish, Arctic, and Austrian. TREM2 expression and cytokine concentrations spiked in brain tissue, microglia flocked to plaques, neurites swelled, and tau and neurofilament light collected in their cerebrospinal fluid. Notably, microglia surrounding plaques seemed distressed...