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With a $35 million gift from researcher, philanthropist and race car driver Theodore Giovanis, scientists at Johns Hopkins Medicine will study the biological roots of the most fatal aspect of cancer: how it metastasizes, or spreads, through the body.
Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.
Store Fat or Burn It? Targeting a Single Protein Flips the Switch As obesity becomes a growing issue worldwide – nearly tripling over the last-half century – scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain. As reported in Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, PhD, and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, ...
Credit: UCSF As obesity becomes a growing issue worldwide — nearly tripling over the last-half century — scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain. As reported in Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, Ph.D., and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if a...
As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsize role in weight gain.