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Although the novel, anti-amyloid treatment gantenerumab was well tolerated, it failed to meet the primary endpoints of slowing clinical decline in the phase 3 Graduate I and II trials.
If children and young people have already developed metabolic imbalances (diabetic ketoacidosis) at the time of diagnosis of type 1 diabetes (T1D), this can result in complications such as extended stays in hospital, poorer long-term control of blood sugar levels, brain edema, or even a higher mortality rate.
The scoring system could assist with accurate severity assessment and choice of medical treatment.
Two related studies, one in humans and the other in rats, found that the cardiovascular effects of cigarettes and e-cigarettes are strikingly similar, and these harmful effects on blood vessel function are likely caused by airway irritation due to inhalation of a foreign substance, rather than a specific component of the cigarette smoke or e-cigarette vapor (aerosol), according to new research published today in the American Heart Association's peer-reviewed journal Arteriosclerosis, Thrombosis and Vascular Biology.
An increase in intracranial pressure (ICP) is a dangerous condition that can be caused by brain bleeds, a brain tumor, cerebral edema, traumatic brain injury, and hydrocephalus.