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Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics.
Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.
Researchers investigated the reasons for the rapid advent of SARS-CoV-2 XBB.1.5, a sublineage of the Omicron recombinant mutant XBB in the USA.
Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.
Researchers characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BQ.1.1 sub-variant.