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Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses. ....

Genomics Industry Focus , Avian Influenza , Binding Affinity ,

Antiviral activity of natural flavonoids against various coronaviruses

A recent study describes the binding affinity and docking sites of several natural compounds, as well as their inhibitory activity against 3CLpro. ....

Kitreel Shutterstock , Image Credit , Discovery Industry Focus , Antiviral Drug , Coronavirus Disease Covid 19 , Binding Affinity , Covid 19 , N Vitro , Ibonucleic Acid , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies. ....

Industry Focus , Coronavirus Disease Covid 19 , Ars Cov 2 , Amino Acid , Binding Affinity , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Exploring the infectivity, transmissibility, and immunological resistance characteristics of SARS-CoV-2 Omicron XBB.1.5 strain

Researchers performed an epidemic dynamic analysis to assess the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC)’s sub-VOC XBB.1.5 characteristics. ....

United States , Ztudio Shutterstock , Industry Focus , Image Credit , Coronavirus Disease Covid 19 , Ars Cov 2 , Binding Affinity , Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants. ....

Scientific Reports , Industry Focus , Coronavirus Disease Covid 19 , Covid 19 , Amino Acid , Ngiotensin Converting Enzyme 2 , Binding Affinity , N Vitro , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,