Page 48 - Biochemistry News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Researchers have identified a critical mechanism that allows deadly bacteria to gain resistance to antibiotics. The findings offer a potential new drug target in the search for effective new antibiotics as we face the growing threat of antimicrobial resistance (AMR) and infections caused by bacterial pathogens. The study investigated quinolone antibiotics which are used to treat a range of bacterial infections, including TB (tuberculosis). Quinolones work by inhibiting bacterial enzymes, gyrase and topoisomerase IV, thereby preventing DNA replication and RNA synthesis essential to growth. ...

 E-Mail IMAGE: Robert Anholt and Trudy Mackay in a lab holding a test tube containing Drosophila melanogaster, the common fruit fly. view more  Credit: Clemson University College of Science Researchers Trudy Mackay and Robert Anholt of the Clemson University Center for Human Genetics have joined forces with an international consortium intended to drive research that will shape regulation and policy on chemical safety without the use of animal testing. Mackay, an internationally renowned scientist and director of the Center for Human Genetics (CHG), will team with Anholt to explore ...

 E-Mail A major research project to shape regulation and policy on chemical safety without the use of animal testing has been launched with the aid of €19.3M funding from the European Commission. Led by the University of Birmingham and involving 15 European and US organisations, PrecisionTox aims to protect human health from the toxic effects of chemicals found in people's homes, food and the environment. The consortium will use genetics, genomics, metabolomics and the study of evolution to investigate the toxicity of hundreds of chemicals and explore how they disrupt the biological proces...

 E-Mail IMAGE: A team at the University of Tsukuba has discovered that spraying plant leaves with high concentrations of the antioxidant ascorbic acid (vitamin C) can dramatically increase the yield of foreign... view more  Credit: University of Tsukuba Tsukuba, Japan - Producing high-value pharmaceutical proteins in plants--sometimes called "molecular pharming"--offers advantages over some other manufacturing methods, notably the low cost and ease of scaling up production to meet demand. But expressing large quantities of "foreign" proteins in plants can also sometimes lead to prob...

 E-Mail HOUSTON, BOSTON and GHENT, Belgium - The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Orionis Biosciences today announced the launch of Project Helios, a research collaboration designed to unlock new drug development opportunities through genome-scale mapping of drug-target interactions. Combining Orionis' unique high-throughput drug discovery technologies with the Therapeutics Discovery division's expertise in small-molecule therapies and translational biology, Project Helios aims to create an unparalleled collection of drug-target interaction ...