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IIT Madras researchers find new method to make AIDS drug more effective

IIT Madras researchers find new method to make AIDS drug more effective
The findings of their study, published in Biochemistry, the peer-review Journal of the American Chemical Society, say that introducing electrostatic interaction sites on potential drug molecules can enhance the efficacy of the antiviral drug against the HIV virus
Joe C Mathew | February 18, 2021 | Updated 14:15 IST
IIT Madras (Image: PTI)
Researchers at the Indian Institute of Technology, Madras claim to have found a novel way to make HIV/AIDS drugs more effective. The findings of their study, published in Biochemistry, the peer-review Journal of the American Chemical Society, say that introducing electrostatic interaction sites on potential drug molecules can enhance the efficacy of the antiviral drug against the HIV virus. The research was led by Prof. Sanjib Senapati, Department of Biotechnology, IIT Madras, along with research scholars Mohammed Ahsan and Chinmai Pindi. ....

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Scientists identify over 140,000 virus species in the human gut

Viruses are the most numerous biological entities on the planet. Now researchers at the Wellcome Sanger Institute and EMBL s European Bioinformatics Institute (EMBL-EBI) have identified over 140,000 viral species living in the human gut, more than half of which have never been seen before. ....

United Kingdom , Trevor Lawley , Matthew Midgley , Alexandre Almeida , Luisf Camarillo Guerrero , European Bioinformatics Institute , National Human Genome Research Institute , Wellcome Sanger Institute , Bioinformatics Institute , Inflammatory Bowel Disease , Postdoctoral Fellow , Gut Phage Database , Sanger Institute , Human Genome Research Institute , Wellcome Genome Campus , ஒன்றுபட்டது கிஂக்டம் , ட்ரெவர் லாலி , மேத்யூ மிட்லே , அலெக்ஸாண்ட்ரே அல்மேடா , ஐரோப்பிய உயிர் தகவலியல் நிறுவனம் , தேசிய மனிதன் மரபணு ஆராய்ச்சி நிறுவனம் , வெல்கம் சாங்கர் நிறுவனம் , உயிர் தகவலியல் நிறுவனம் , அழற்சி குடல் நோய் , போஸ்ட்‌டாக்டொரல் சக , குடல் ஃபேஜ் தரவுத்தளம் ,

IIT Madras researchers show the way to more effective drugs to treat HIV-AIDS

IIT Madras researchers show the way to more effective drugs to treat HIV-AIDS
indiatoday.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from indiatoday.in Daily Mail and Mail on Sunday newspapers.

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Finding coronavirus's helper proteins

EMBL scientists identify human proteins hijacked by coronavirus, offering potential drug targets
EMBL scientists used a biophysical method called thermal proteome profiling (TPP) to gain a comprehensive overview of which human proteins are functionally altered at different times during SARS-CoV-2 infection. Credit: Holly Joynes/EMBL
A group of scientists led by EMBL’s Mikhail Savitski, Nassos Typas, and Pedro Beltrao, and collaborator Steeve Boulant at Heidelberg University Hospital, have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
The researchers used a biophysical method called thermal proteome profiling (TPP) to gain a comprehensive overview of which human proteins are functionally altered during SARS-CoV-2 infection. TPP monitors protein amounts and denaturation temperatures – the points at which proteins heat up so much that they lose their ....

Baden Wuberg , Holly Joynes , Mikhail Savitski , Nassos Typas , Pedro Beltrao , Technical University Of Munich , European Bioinformatics Institute , Steeve Boulant At Heidelberg University Hospital , Heidelberg University Hospital , German Cancer Research Center , Steeve Boulant , Genome Biology Unit , Core Facility , Bioinformatics Institute , Technical University , University Of Munich , Cancer Research , Corona Virus , ஹோலி ஜாய்ன்ஸ் , பேடரோ பெல்ட்ராவ் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் முனிச் , ஐரோப்பிய உயிர் தகவலியல் நிறுவனம் , ஹைடெல்பெர்க் பல்கலைக்கழகம் மருத்துவமனை , ஜெர்மன் புற்றுநோய் ஆராய்ச்சி மையம் , மரபணு உயிரியல் அலகு , கோர் வசதி ,

Global Proteomics Partnering Terms and Agreements Analysis Report 2020

Global Proteomics Partnering Terms and Agreements Analysis Report 2020
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The Global Proteomics Partnering Terms and Agreements 2010 to 2020 report provides an understanding and access to the Proteomics partnering deals and agreements entered into by the worlds leading healthcare companies.
The report provides a detailed understanding and analysis of how and why companies enter Proteomics partnering deals. The majority of deals are early development stage whereby the licensee obtains a right or an option right to license the licensors Proteomics technology or product candidates. These deals tend to be multicomponent, starting with collaborative R&D, and commercialization of outcomes. ....

United Kingdom , Ch Ungch Ong Bukto , South Korea , Kyongsang Bukto , United States , Mecklenburg Vorpommern , Eucodis Bioscience , Caprion Biosciences , Therapure Biopharma , Bionova Cientifica , Cyclenium Pharma , Olink Bioscience , Eli Lilly , Bristol Myers Squibb , Wafergen Biosystems , Dimerix Biosciences , Oxford Biotherapeutics , Cisbio Bioassays , Selecta Biosciences , Laura Wood , Xbrane Bioscience , Analytical Testing Laboratory , University Of Rostock , National Institute Of Allergy , Boehringer Ingelheim , University Of British Columbia ,