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Targeting gene-fibroblast interaction offers hope for treatment-resistant colon cancer

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance." ....

T Ai Pei , Vijesh Kumar Yadav , Chi Tai Yeh , Tung Cheng Chang , Kuang Tai Kuo , Ying Wei Chen , Shiue Wei Lai , Taipei Medical University Shuang , National Taitung University , Taipei Medical University , Taipei National Defense Medical Center , Yi Chiao Cheng , Kee Thai Kiu , Min Hsuan Yen , National Defense Medical Center , Taipei Medical University Shuang Ho Hospital , Colorectal Cancer , Transcription Factors ,

UPDATE - Gain Therapeutics' GT-02287 Completely Restores

Data presented at 20th WORLDSymposium™ show progressive reversal of motor deficit and corresponding reduction of neurodegeneration biomarker NfL to level. ....

San Diego , United States , Elio Ambrosio , Nic Johnson , Matthias Alder , Gain Therapeutics Inc , Exchange Commission On , Silverstein Foundation For Parkinson , Michaelj Fox Foundation For Parkinson Research , Exchange Commission , Drug Administration , Company Annual Report On Form , Gain Therapeutic Chief Executive , Neurofilament Light Chain , Silverstein Foundation , Gain Therapeutics , Site Directed Enzyme Enhancement Therapy , Private Securities Litigation Reform Act , Annual Report , Nasdaq Ganx , Gain Therapeutics , Arkinson 39 Sdisease ,

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). ....

Liisa Selin , Anna Gil , Umass Chan Medical School , Chan Medical , Chan Medical School , Chronic Fatigue Syndrome , Immune System , Medical School , Myalgic Encephalomyelitis , T Cell ,

Berry consumption shown to lower stress-related disease risk in US adults

The association between berry consumption and physiological dysregulation from stress responses. ....

United States , Bojsha Shutterstock , National Health , Nutrition Examination , Nutrition Examination Survey , Berry Consumption , Allostatic Load ,

Study Reveals Disparities in CRC Biomarker Testing Trends

Testing trends are consistent with guideline recommendations and FDA approvals, but demographic disparities exist. ....

United States , Hannahr Robinson , University Of Colorado School Medicine , National Comprehensive Cancer Network , Flatiron Health , Drug Administration , Comprehensive Cancer Network , Colorado School , Cancers Symposium , Metastatic Colorectal Cancer , Metastatic Crc , Etastatic Colorectal Cancer Mcrc , Iological Marker , Ulti Biomarker Disease Activity , Multibiomarker Disease Activity , Malignant Melanoma , Social Determinants Of Health , Social Determinants Of Health Sdoh , Colorectal Cancer , Colorectal Cancer Crc , Clinical Guidelines ,