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Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy. ....

Western Australia , Florent Ginhoux , Ankur Sharma , National Cancer Centre Singapore , Lab Head Of The Onco , Harry Perkins Institute Of Medical Research , Singapore Immunology Network , Research Council , Translational Research Investigator Award , Fetal Ecosystem Laboratory , Biomedical Research Council , National Research Foundation Singapore , Singapore National Research Foundation Senior Investigatorship , National Health , Research Future Fund , Agency For Science , Harry Perkins Institute , Medical Research , Nature Cancer , Slab Head , Onco Fetal Ecosystem Laboratory , Associate Professor Florent Ginhoux , Senior Principal Investigator , Immunology Network , Professor Pierce Chow , Senior Consultant Surgeon ,

Primary care providers may be the key to accelerating delivery of emerging Alzheimer's treatments

There is substantial geographic variation across the U.S. health care system to diagnose and treat early-stage Alzheimer's disease with disease-modifying therapies, and engaging primary care providers in the effort may be a key to accelerating delivery of emerging new treatments, according to a new RAND report. ....

United States , Jodi Liu , Drug Administration , Rand Corporation , Primary Care , Lzheimer 39s Disease , Health Care ,

Study identifies plasma markers linked to mental health in young adults

Study in "Translational Psychiatry" explores plasma proteins related to the p-factor in young adults, revealing potential biomarkers for overall mental health status and insights into common underlying factors of mental health disorders. ....

Yuliia Shutterstock , Translational Psychiatry , Pavlova Yuliia , Finnish Central Population Registry , Human Plasma Proteome Database , Mental Health ,

Interventions for mood show promise for the management of IBD

Researchers performed a meta-analysis to explore the impact of mood interventions on inflammatory disease activity in inflammatory bowel disease (IBD). ....

Global Health , Image Credit , Cochrane Handbook , Mental Health , Inflammatory Bowel Disease , Inflammatory Disease ,

Monitoring Treatment Response in Treat-to-Target in CD

Experts continue the discussion on treat-to-target in CD, highlighting monitoring treatment response. ....

Miguel Regueiro , David Rubin , Sarah Horst , Remo Panaccione , Marla Dubinsky , Crohn X27s Disease , Treat To Target , Treatment Response , Intestinal Ultrasounds ,