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FDA Says No to Accelerated Approval for Alzheimer's Drug

The FDA has denied accelerated approval of donanemab for early Alzheimer s disease, but will evaluate traditional approval when more data are released from the phase 3 TRAILBLAZER ALZ trial. ....

Howard Fillit , Eli Lilly , Alzheimer Association , Alzheimer Drug Discovery Foundation , Drug Administration , Medscape Medical , Drug Discovery Foundation , Alzheimers Disease , Lzheimer Disease , Amyloid Beta , Monoclonal Antibody , Amyloid Plaque , Iological Marker , Drug Development , Us Food And Drug Administration , Nited States Food And Drug Administration , Antidementia Agents ,

PCSK9 Inhibitors for Severe COVID? Pilot Trial Signals Benefit

The drugs effects go beyond LDL-lowering in ways that might potentially benefit hospitalized patients with COVID-19, at least those who are sickest, preliminary results suggest. ....

New York , United States , Ann Arbor , Kujawsko Pomorskie , Elianop Navarese , Roberts Rosenson , Icahn School Of Medicine At Mount Sinai , Journal Of The American College Cardiology , Medscape Coronavirus Resource Center , Nicolaus Copernicus University , University Of Michigan , Coronavirus Resource , American College , Icahn School , Mount Sinai , 019 Novel Coronavirus , 019 Ncov , Uhan Coronavirus , Uman Coronavirus Hku1 , Uman Coronavirus Oc43 , Cov Oc43 , Uman Coronavirus 229e , Cov 229e , Ipid Management , Roprotein Convertase Subtilisin Kexin Type 9 , Viral Pneumonia ,

Longest Overall Survival Ever Seen in Advanced Gastric Cancer

The combination of zolbetuximab plus chemotherapy produced one of the longest overall survival outcomes ever seen for patients with advanced caludin18.2+ gastric or gastroesophageal junction cancer. ....

United States , University Of Texas , Kohei Shitara , Davidh Wang , Astellas Pharma Inc , American Society Of Clinical Oncology , National Cancer Center Hospital East Kashiwa City , Department Of Gastrointestinal Oncology , Ganymed Pharmaceuticals , Gastrointestinal Oncology , Gastrointestinal Cancers Symposium , American Society , Internal Medicine , Texas Southwestern Medical Center , Medscape Medical News , Astellas Pharma , Cancers Symposium , Noncolorectal Gastrointestinal Cancer , Oncolorectal Gi Cancer , Biologic Therapy , Gastric Cancer , Alignant Stomach Neoplasm , Alignant Neoplasia , Targeted Therapy , Monoclonal Antibody , Iological Marker ,

How does the brain change with age?

Researchers discussed cellular hallmarks of brain aging and therapeutic interventions to rejuvenate cognitive brain functions. ....

Nature Neuroscience , Industry Focus , Ognitive Function , Growth Factor , Eurodegenerative Disease ,

Partial genetic reprogramming might extend lifespan and reverse aging in old mice

Researchers performed age-reversing experiments, in vivo and in vitro, in progeroid mice using gene therapy. ....

Aimee Molineux , Neha Mathur , Neha Mathurjan , Noah Davidsohn , Reverses Age Related Changes , Image Credit , Genomics Industry Focus , Lifespan Uber Clock , Chief Scientific Officer , Gene Therapy , N Vitro , N Vivo , Transcription Factors ,