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Enzyme released by immune cells may play role in depression

Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors.

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Stress-Drawn Immune Cells Can Control Emotional Behaviors: Study

Stress-Drawn Immune Cells Can Control Emotional Behaviors: Study
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Mount Sinai study shows that circulating immu

<p><em>Findings shed light on mechanisms underlying psychosocial stress and depression susceptibility</em></p>

Long-island , Florida , United-states , New-york , Westchester , Scott-russo , Flurin-cathomas , Leon-levy , Mount-sinai-health-system , Body-research-center-at-mount-sinai , Health-system , Method-of-research

Mount Sinai Study Shows That Circulating Immune Cells Drawn to the Brain During Stress Can Control Emotional Behaviors

Findings shed light on mechanisms underlying psychosocial stress and depression susceptibility

New-york , United-states , Scott-russo , Flurin-cathomas , Leon-levy , Body-research-center-at-mount-sinai , Body-research-center , Mount-sinai , Brain-body-research-center , Mount-sinai-professor , Affective-neuroscience , Leon-levy-director

Mount Sinai Study Shows That Circulating Immune Cells Drawn to the Brain During Stress Can Control Emotional Behaviors

Findings shed light on mechanisms underlying psychosocial stress and depression susceptibility

New-york , United-states , Scott-russo , Flurin-cathomas , Leon-levy , Body-research-center-at-mount-sinai , Body-research-center , Mount-sinai , Brain-body-research-center , Mount-sinai-professor , Affective-neuroscience , Leon-levy-director

Hyperactivated brain cells following social trauma impair social reward and promote social avoidance

Past social trauma is encoded by a population of stress/threat-responsive brain cells that become hyperactivated during subsequent interaction with non-threatening social targets. As a consequence, previously rewarding social targets are now perceived as social threats, which promotes generalized social avoidance and impaired social reward processing that can contribute to psychiatric disorders, according to a study conducted by researchers at the Brain and Body Research Center at Mount Sinai and published November 30 in Nature.

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