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Functional magnetic resonance imaging (fMRI) enables non-invasive access to the awake, behaving human brain. By tracking whole-brain signals across a diverse range of cognitive and behavioural states or mapping differences associated with specific traits or clinical conditions, fMRI has advanced our understanding of brain function and its links to both normal and atypical behaviour. Despite this headway, progress in human cognitive neuroscience that uses fMRI has been relatively isolated from rapid advances in other subdomains of neuroscience, which themselves are also somewhat siloed from one...

Fossil endocasts record features of brains from the past: size, shape, vasculature, and gyrification. These data, alongside experimental and comparative evidence, are needed to resolve questions about brain energetics, cognitive specializations, and developmental plasticity. Through the application of interdisciplinary techniques to the fossil record, paleoneurology has been leading major innovations. Neuroimaging is shedding light on fossil brain organization and behaviors. Inferences about the development and physiology of the brains of extinct species can be experimentally investigated thro...

Creativity is an essential cognitive ability linked to all areas of our everyday functioning. Thus, finding a way to enhance it is of broad interest. A large number of anecdotal reports suggest that the consumption of psychedelic drugs can enhance creative thinking; however, scientific evidence is lacking. Following a double-blind, placebo-controlled, parallel-group design, we demonstrated that psilocybin (0.17 mg/kg) induced a time- and construct-related differentiation of effects on creative thinking. Acutely, psilocybin increased ratings of (spontaneous) creative insights, while decre...

Brain mapping aims to uncover the relationship between the structure and function of the brain.

Torrisi, S, Gorka, AX, Gonzalez-Castillo, J, Balderston, NL, Grillon, C, & Ernst, M (2018). Extended amygdala connectivity changes during sustained shock anticipation. Translational Psychiatry. 8(33) 2017 Balderston, NL, Liu, J, Roberson-Nay, R, Ernst, M, & Grillon, C (2017). The relationship between dlPFC activity during unpredictable threat and CO2-induced panic symptoms. Translational Psychiatry, 7(12), 1266. Balderston NL, Hsiung A, Ernst M, Grillon C (2017) The effect of threat on right dlPFC activity during behavioral pattern separation. J Neurosci 37:0717–17. Balderston NL, Hsiung ...