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"The profit taking has been broad based amid softer global cues," said Pankaj Pandey, head of research at ICICI Securities. "Nifty is also struggling to cross the psychological levels of 22,000 due to lack of near-term triggers."
The popular video-sharing app said it had walled off American data in so-called Project Texas, but employees say data is still sometimes shared with its China-based parent.
Spot gold edged 0.1% higher to $2,030.87 per ounce by 0116 GMT.
As the US carried out its fifth airstrike against Houthi targets in Yemen on Thursday, the Iran-backed rebel group quickly launched two anti-ship ballistic missiles at a US-owned chemical tanker, though no injuries or damages were reported.
The Indian rupee closed marginally higher on Wednesday, supported by dollar sales from foreign banks, even as most of its Asian peers fell pressured by a recovery in the U.S. dollar index.