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Welcome To IANS Live - SCIENCE AND TECHNOLOGY - Novel gene editor to correct disease-causing mutations

Welcome To IANS Live - SCIENCE AND TECHNOLOGY - Novel gene editor to correct disease-causing mutations
ianslive.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ianslive.in Daily Mail and Mail on Sunday newspapers.

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C-to-G Base Editor Developed by Singapore Genome Institute

C-to-G Base Editor Developed by Singapore Genome Institute
March 12, 2021
Source: CIPhotos / iStock / Getty Images Plus
A C-to-G Base Editor (CGBE), using CRISPR, has been developed by a team of researchers from the Agency for Science, Technology and Research’s (A STAR) Genome Institute of Singapore (GIS). This advance opens up treatment options for approximately 40% of the single-base substitutions associated with human diseases such as cystic fibrosis, cardiovascular diseases, musculoskeletal diseases, and neurological disorders.
One in seventeen people in the world suffers from some type of genetic disorder. Mutations responsible for these disorders can be caused by multiple mutagens – from sunlight to spontaneous errors. The most common mutation by far is the single-based substitution, in which a single-base in the DNA (such as G) is replaced by another base (such as C). ....

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Singapore scientists develop novel gene editor to correct disease-causing mutations

Singapore scientists develop novel gene editor to correct disease-causing mutations
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Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders
A team of researchers from the Agency for Science, Technology and Research s (A STAR) Genome Institute of Singapore (GIS) have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders. Their research was published in
Nature Communications on 2 March 2021.
One in seventeen people in the world suffers from some type of genetic disorder. Chances are, you or someone you know - a relative, friend, or colleague - is one of approximately 450 million people affected worldwide. Mutations responsible for these disorders can be caused by multiple mutagens - from sunlight to spontaneous errors in your cells. The most common mutation by far is the single-based substitution, in which a single-base in the DNA (such as G) is replaced by another base (such as C). Countless cystic fibrosis patients worldwide have C instead of G, leading to ....

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