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minneapolis braces for the start of the murder trial for the former officer seen kneeling on george floyd the mayor calling it the most significant trial in the city's history. royal reveal the queen calls for unity ahead of prince harry and meghan markle's controversial interview airing tonight will her majesty watch. and like mother, like daughter, the inspiring women who earned their medical degrees together now working on the front line of the covid crisis. >> announcer: this is "nbc nightly news" with kate snow. >> good evening. the governor of new york state is under increa...

Tonight, the new covid shock. As america records its biggest oneday surge in cases since this pandemic began. More than 50,000 cases reported in one day. Dr. Anthony fauci warning we are at risk of losing control. At the same time, President Trump insists they are putting out the flames. Tonight, we go inside one Florida Hospital as doctors and nurses suit up for battle. 10,000 new infections in florida today. And their youngest victim yet, just 11 years old. Disturbing reports about young people throwing Covid Parties in alabama to see who gets it first. A 4monthold hospitalized there. Hospit...

In the thick of respiratory season and cedar fever, Austin Public Health officials are reporting upticks in local COVID-19 cases.

>> reporter: less than 50% of adults and children have been the numbers are even lower for covid. the case counts so concerning, at least ten states and washington, d.c., have reinstated mask mandates in some hospitals. >> right now, what we are focused on is making sure that if the respiratory situation gets even worse, that the hospitals will be able to scale up and respond appropriately. >> reporter: the cdc is encouraging those who have not received a flu shot or an updated covid vaccine to do so, saying it is not too late and it is the best protection against severe illness. major? >> maj...

A new variant, known as Pirola, is poised to attack. Little is known about its severity. Despite a sense of fatigue, the public should remain vigilant. Read more.