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Jeff Bezos uses "regret minimization framework" to help him make tough decisions.  It's the idea that we should live our lives minimizing regrets.  To implement this strategy in your own life, it's important not to be afraid of failure.  An oft-cited interview with Jeff Bezos gives us some insight into how the Amazon CEO, and soon-to-be executive chairman when he steps down in Q3, makes big decisions.  In the interview, which was conducted by the Academy of Achievement, Bezos discusses his "regret minimization framework." (We first came across this snippet of the interview in Jenny Blake'...

 E-Mail (Boston)--There have been great advances in treating melanoma over the past five years, however, even with these treatments many patients quickly develop drug resistance and die from their disease. A new study from Boston University School of Medicine (BUSM) has discovered that a drug (YK-4-279) that was previously created to target one specific type of protein has much broader use against a family of proteins that act to promote melanoma. "We find that this drug inhibited melanoma from becoming more aggressive in human cells and in experimental models. We also found a specific pathw...

Pablo Santaeufemia of Bridge for Billions: “Entrepreneurship and business systems” …We need to first accept and then analyse our rigged systems to detect inefficiencies and rooted discrimination. Most of our systems today, pick any: our educational systems, social security systems, electrification systems, taxation systems… All were designed by a generation that no longer lives or for a world that no longer exists. Hence, it is […] The Thrive Global Community welcomes voices from many spheres on our open platform. We publish pieces as written by outside contributors with a wide rang...

Boutique Washington, D.C. office building sold for $58.5M WASHINGTON, D.C., Jan. 6, 2021 -JLL Capital Markets announced today that it has closed the $58.5 million leasehold sale of 1717 Rhode Island, a 157,050-square-foot boutique office building in the heart of downtown Washington, D.C. JLL marketed the property on behalf of the seller, BentallGreenOak. Tritower Financial Group purchased the asset. 1717 Rhode Island provides a first-class amenity package that includes private terraces on the upper floors, a fitness center, two-story lobby and a three-level parking garage. The property is 86 ...

Print this article The prospective impact of the Pfizer and Moderna COVID-19 vaccines on public and economic health is virtually incalculable. But the fact that two private pharmaceutical firms are the agents of discovery and production of such a profoundly important public good should not be taken for granted. Two publicly traded companies, putting their own funds at risk, will, we hope, deliver social benefits worth trillions in return for profits in the low billions. This flies in the face of an emergent narrative about traditional, for-profit firms: that absent clearly set out social and...