Page 7 - Cell Biol News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Researchers found that the activity of a particular enzyme in the blood was significantly higher in horses with lymphoma.

Stacy Blain A breast cancer researcher at SUNY Downstate in Brooklyn has sued the university for sex discrimination and retaliation after an institutional investigation found she committed research misconduct.  Stacy Blain, an associate professor in the departments of pediatrics and cell biology at Downstate, has alleged that the university violated the Equal Pay Act by…

If you haven’t heard about spermadine for longevity already, then it’s name you’ll become more familiar with after reading this article

Clinical signs of cancer in horses can be vague, and confirming a diagnosis in systemic cases can be challenging.

Although targeting BRAF mutants with RAF inhibitors has achieved promising outcomes in cancer therapy, drug resistance remains a remarkable challenge, and underlying molecular mechanisms are not fully understood. Here, we characterized a previously unknown group of oncogenic BRAF mutants with in-frame insertions (LLRins506 or VLRins506) of αC-β4 loop. Using structure modeling and molecular dynamics simulation, we found that these insertions formed a large hydrophobic network that stabilizes R-spine and thus triggers the catalytic activity of BRAF. Furthermore, these insertions disrupted BRAF...