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Expelling cancer by squeezing out rogue cells - Vimarsana News

Expelling cancer by squeezing out rogue cells

May 5, 2021 11:00am MIT biologists reported that the cell elimination process called cell extrusion could offer new insights into stopping cancer. (Vivek Dwivedi) Cancer cells multiply out of control because they're able to escape a mechanism known as programed cell death. But scientists at the Massachusetts Institute of Technology (MIT) and King’s College London have uncovered key functions of another pathway with a long evolutionary history that the body uses to dispose of those rogue cells. During this process, called cell extrusion, cells are squeezed out of the lining of tissu...

Scientists find a new anti-hepatic fibrosis drug target - Vimarsana News

Scientists find a new anti-hepatic fibrosis drug target

 E-Mail Scientists from Russia and Italy studied a new axis of the pathway that prevents the development of liver fibrosis. The role of GILZ protein in curbing the disease progression was shown in a study using mice models and confirmed by clinical data. These findings can be used in the treatment of liver fibrosis in humans. The research was published in the journal Cell Death & Disease. Fibrosis combines an overgrowth of connective tissue and a decline in the liver function that can be caused by a viral infection, alcohol intoxication, autoimmune diseases or other liver disorders. If left...

Enzyme that could help 700 million people worldwide - Vimarsana News

Enzyme that could help 700 million people worldwide

Date Time Enzyme that could help 700 million people worldwide University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide. This enzyme, NEDD4-2, is critical for kidney health, says UniSA Centre for Cancer Biology scientist Dr Jantina Manning in a new paper published this month in Cell Death & Disease. The early career researcher and her colleagues, including 2020 SA Scientist of the Year Professor Sharad Kumar, have shown in an animal study the correlation between a high salt diet, l...

The enzyme that could help 700 million people worldwide - Vimarsana News

The enzyme that could help 700 million people worldwide

Loading video... VIDEO: Approximately 700 million people worldwide now live with chronic kidney disease (CKD), largely due to a huge spike in obesity and type 2 diabetes in recent decades. Salt and high... view more  Credit: University of South Australia University of South Australia researchers have identified an enzyme that may help to curb chronic kidney disease, which affects approximately 700 million people worldwide. This enzyme, NEDD4-2, is critical for kidney health, says UniSA Centre for Cancer Biology scientist Dr Jantina Manning in a new paper published this month in Cell D...

Important factor in the development of dendritic cells identified - Vimarsana News

Important factor in the development of dendritic cells identified

 E-Mail The human immune system comprises functionally specialised cellular defence mechanisms that protect the body against disease. These include the dendritic cells. Their main function is to present antigens to other immune cells, especially T cells, thereby activating a primary immune response. Dendritic cells are divided into Type 1 (DC1) and Type 2 (DC2) dendritic cells. Each type fulfils different functions: DC1 provide an immune response to bacteria and viruses, DC2 protect against fungal or parasitic infections. In a recent study conducted at MedUni Vienna's Institute of Cancer Res...