Page 27 - Cell Death News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Parkinson’s UK, University of Sheffield to develop new Parkinson’s drug Parkinson's UK, the largest charitable funder of Parkinson's research in Europe, is investing up to £1.2 million into a pioneering one-year project in partnership with the University of Sheffield. The project aims to refine a molecule that could be developed into a drug to protect dopamine-producing brain cells and slow down the progression of Parkinson's. The funding boost comes via the charity's Parkinson's Virtual Biotech initiative, which is plugging the funding gap in drug development and fast-tracking the devel...

Study shows how mutant huntingtin protein triggers brain cell death In 1993, scientists discovered that a single mutated gene, HTT, caused Huntington's disease, raising high hopes for a quick cure. Yet today, there's still no approved treatment. One difficulty has been a limited understanding of how the mutant huntingtin protein sets off brain cell death, says neuroscientist Srinivasa Subramaniam, Ph.D., of Scripps Research, Florida. In a new study published in Nature Communications on Friday, Subramaniam's group has shown that the mutated huntingtin protein slows brain cells' protein-buildi...

Discussion There are several therapeutic approaches to bio-functional foods against cardiovascular diseases, both in experimental and clinical studies. Germinated Brown Rice (GBR) exerted its protective properties on cardiovascular diseases and related-cardiovascular metabolism dysfunction, including hypertension, hyperlipidemia, and diabetes. Here, this is the first study to represent the cardioprotective effect of GBR on cardiomyocyte-simulated I/R injury. The significant findings in this study indicated that simulation of I/R promoted the percentage of cell death and total cell apoptosis. ...

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection Apoptosis is a form of programmed cell death, which occurs in cells that are irreparably damaged or in cells infected by some viruses. This mechanism is extremely important in limiting a virus’s replication and its spread to other neighboring cells. A new paper in the journal Lifepresents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells. Colorized scanning electron micrograph of an apoptotic cell (blue) infected with SARS-COV-2 virus particles (red), i...

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph Disease (MJD), describes the most common form of dominantly inherited ataxia in many populations worldwide, including Hong Kong and mainland China. SCA3 or MJD patients often present problems with gait and balance, blurred vision, and speech difficulties. The symptoms are progressive, and patients may eventually decline into a bed-ridden state. To date, SCA3 or MJD remains an incurable disorder. Collaborating with the University of Oxford, ...