Stay updated with breaking news from Cell Death. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to keep cancer cells from using DNA break repair pathways.
Cellular survival after radiation exposure depends on the specific protein behavior Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others. Scientists have known these differences involve the protein p53, a well-studied tumor-suppressor protein that initiates a cell's auto-destruct programs. Yet, levels of this sentinel protein are often similar in tissues with vastly different sensitivities to radiation, posing the question: How is p53 involved? A new study by researchers in the ...
100+ pipeline drugs in the Diffuse Large B Cell Lymphoma pipeline landscape. It comprises DLBCL pipeline drug profiles, including clinical and non-clinical stage products. It also includes the Diffuse Large B Cell Lymphoma therapeutics assessment by product type, stage, route of administration, and molecule type, and further highlights the inactive DLBCL pipeline products. Some of the significant Highlights Several prominent companies such as ADC Therapeutics, BeiGene, Nordic Nanovector, bluebird bio, Celgene, GlaxoSmithKline, AbbVie, Roche and many others are working to assess ch...
New method reveals how pharmaceuticals induce cancer cell death Cancer cells are smart when it comes to anti-cancer drugs, evolving and becoming resistant to even the strongest chemotherapies over time. To combat this evasive behavior, researchers have developed a method named D 2O-probed CANcer Susceptibility Test Ramanometry (D 2O-CANST-R) to see, at single-cell/organelle level, how pharmaceuticals induce cancer cell death and how cancer cells adapt. The research, conducted by the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (CAS), was...
%2c_analyze_by_microscope-Jarun_Ontakrai_8864dd9cfb3b4dff9a913aede7a7c915-620x480.jpg)
Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone.