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Cancer, we are told, is a disease of the genes. It originates in mutations in the DNA. But a paper published by a Weizmann Institute group in Cell Reports flips that idea sideways by about 90 degrees: For at least some types of the disease, the healthy, non-mutated version of a gene is no less of a driving force behind the development of cancer than its mutated form.
While patient factors are critical in determining mortality risks, specific genes are linked to golden staph's antibiotic resistance, along with the bacteria's ability to linger in the blood.
A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.
<p>Scientists at Gladstone Institutes have discovered that APOE4-producing neurons release an immune signaling molecule called HMGB1 at much higher rates than neurons producing other APOE variants. Upon release, HMGB1 activates brain immune cells called microglia, which then trigger inflammation and the degeneration of neurons.</p>
Duke scientists optimistic about early results for new type of coronavirus vaccine.