Circulating Tumour Cells News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Stay updated with breaking news from Circulating tumour cells. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Top News In Circulating Tumour Cells Today - Breaking & Trending Today

"Circulating Tumour Cell Associated MicroRNA Profiles Change during Che" by Stephanie H. Lim, Wei Chua et al.

Locally advanced rectal cancer (LARC) has traditionally been treated with trimodality therapy consisting of neoadjuvant radiation +/− chemotherapy, surgery, and adjuvant chemotherapy. There is currently a clinical need for biomarkers to predict treatment response and outcomes, especially during neoadjuvant therapy. Liquid biopsies in the form of circulating tumour cells (CTCs) and circulating nucleic acids in particular microRNAs (miRNA) are novel, the latter also being highly stable and clinically relevant regulators of disease. We studied a prospective cohort of 52 patients with LARC, and obtained samples at baseline, during treatment, and post-treatment. We enumerated CTCs during chemoradiation at these three time-points, using the IsofluxTM (Fluxion Biosciences Inc., Alameda, CA, USA) CTC Isolation and detection platform. We then subjected the isolated CTCs to miRNA expression analyses, using a panel of 106 miRNA candidates. We identified CTCs in 73% of patients at baseline; numb ....

United States , Isofluxtm Fluxion Biosciences Inc , Fluxion Biosciences Inc , Circulating Tumour Cells , Locally Advanced Rectal Cancer , Predictive Biomarkers ,