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Janssen: New Amivantamab Data from CHRYSALIS Study Show Robust Clinical Activity and Durable Responses in Patients with Metastatic or Unresectable Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Mutations


Janssen: New Amivantamab Data from CHRYSALIS Study Show Robust Clinical Activity and Durable Responses in Patients with Metastatic or Unresectable Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Mutations
FOR EU TRADE AND MEDICAL MEDIA ONLY Not for distribution in the UK and Benelux
The Janssen Pharmaceutical Companies of Johnson Johnson today announced new data from the Phase 1 CHRYSALIS study, which evaluated amivantamab in patients with metastatic or unresectable non-small cell lung cancer (NSCLC) and epidermal growth factor receptor (EGFR) exon 20 insertion mutations whose disease progressed on or after platinum-based chemotherapy.
1 These data were presented for the first time in an oral presentation at the International Association for the Study of Lung Cancer s (IASLC) 2020 World Conference on Lung Cancer (WCLC) Singapore. The key findings showed robust activity and durable responses with a tolerable and manageable safety profile (Abstract #3031) in patien ....

United States , United Kingdom , Noah Reymond , Jennifer Mcintyre , Kostenloser Wertpapierhandel , Christopher Delorefice , J Thorac Oncolo , Joshuak Sabari , Sarah Jones , None Of The Janssen Pharmaceutical Companies , National Cancer Institute , Janssen Biotech Inc , York University Langone Perlmutter Cancer Centre , Janssen Research Development , Janssen Pharmaceutical Companies , Janssen Pharmaceutical Companies Of Johnson , Yuhan Corporation , Exchange Commission , Companies Of Johnson , European Medicines Agency , American Cancer Society , International Association , Lung Cancer , New York University Langone , Perlmutter Cancer Centre , Response Evaluation Criteria ,

Evotec AG: Evotec Starts Clinical Development of Chikungunya Antibody together with NIAID and Leading Academic Research Organisation


Evotec AG: Evotec Starts Clinical Development of Chikungunya Antibody together with NIAID and Leading Academic Research Organisation
DEVELOPMENT OF EVT894 BY EVOTEC TOGETHER WITH ITS PARTNERS NIAID AND DUKE CLINICAL RESEARCH INSTITUTE
ADDRESSING UNMET MEDICAL NEEDS IN GLOBAL HEALTH
HAMBURG, GERMANY / ACCESSWIRE / January 28, 2021 / Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809) today announced that EVT894, a monoclonal antibody to treat and potentially prevent chikungunya virus infections, has entered clinical development.
The Phase I, randomised, double-blind, single centre, single dose escalation study to evaluate the safety, pharmacokinetics, and immunogenicity of EVT894 vs placebo in healthy volunteers (five dose-cohorts of 8 subjects) is sponsored and funded by the National Institute of Allergy and Infectious Diseases ( NIAID ), part of the National Institutes of Health with funds from a Phase I Clinical Trial Units for Therapeutics ....

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