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TGen identifies gene that could explain disparity in COVID-19 effects

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PHOENIX, Ariz. Dec. 15, 2020 The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become.
The study results, recently published in the journal
mSphere, describe a molecule made from DNA miR1307 as a potential dimmer switch that may influence the severity of the disease; why some infected with SARS-CoV-2, the virus that causes COVID-19, have mild or even no symptoms, while others become seriously ill or die.
Led by Nicholas Schork, Ph.D., a Distinguished Professor and Director of TGen s Quantitative Medicine and Systems Biology Division, researchers identified miR1307 by comparing the genetic elements of SARS-Cov-2 with seven other human coronaviruses, some of which merely cause common colds. In addition, they examined the genomes of coronavirus strains known to infect bats, pigs, pangolin ....

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Identifying a gene that could explain disparity in COVID-19 effects

Identifying a gene that could explain disparity in COVID-19 effects
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Nicholas Schork , Agnesp Chan , Translational Genomics Research Institute Tgen , Systems Biology Division , Translational Genomics Research Institute , Distinguished Professor , Quantitative Medicine , Conserved Genomic Terminals , Coevolving Functional Elements , Potential Therapeutic Targets , அமைப்புகள் உயிரியல் பிரிவு , மொழிபெயர்ப்பு மரபியல் ஆராய்ச்சி நிறுவனம் , புகழ்பெற்ற ப்ரொஃபெஸர் , அளவு மருந்து , பொடெந்ஶியல் சிகிச்சை இலக்குகள் ,