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University of Melbourne and Screen Well launch new study examining impact of alcohol use in the screen industry

University of Melbourne and Screen Well launch new study examining impact of alcohol use in the screen industry
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Antoinette Poulton , Ben Steel , Research Council Medical Future Fund , Melbourne School Of Psychological Sciences , University Of Melbourne , National Health , Cognitive Neuroimaging Laboratory , Melbourne School , Psychological Sciences , Screen Well , Actor Wellbeing Study , Medical Research Council Future ,

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia
People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer s disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after age 65, according to Georgetown University Medical Center investigators and colleagues.
The researchers used MRI scans to examine the brain, with a focus on two regions - the hippocampus, which is critical for memory and is often affected in Alzheimer s disease, and the caudate nucleus, which sits deep in the center of the brain and is often affected in people with HIV. Based on the MRI images, they found that connectivity between the two regions was affected by APOE4 in people with HIV. A history of severe immunosuppression further exacerbated the impact o ....

Xiong Jiang , Emily Henderson , Cognitive Neuroimaging Laboratory , Georgetown University Medical Center , Cognitive Neuroimaging , Alzheimer 39s Disease , க்ஷ்ிொன் ஜியாங் , எமிலி ஹென்டர்சன் , அறிவாற்றல் நியூரோஇமேஜிங் ஆய்வகம் , ஜார்ஜ்டவுன் பல்கலைக்கழகம் மருத்துவ மையம் , அறிவாற்றல் நியூரோஇமேஜிங் ,

Immune-compromised people with HIV, APOE4 gene may have a compounded risk for Alzheimer's

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WASHINGTON (Feb. 22, 2021) - People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer s disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after age 65, according to Georgetown University Medical Center investigators and colleagues.
The researchers used MRI scans to examine the brain, with a focus on two regions - the hippocampus, which is critical for memory and is often affected in Alzheimer s disease, and the caudate nucleus, which sits deep in the center of the brain and is often affected in people with HIV. Based on the MRI images, they found that connectivity between the two regions was affected by APOE4 in people with HIV. A history of severe immunosuppression further exacerbated the impact of APOE4. ....

Georgetown University , District Of Columbia , United States , San Diego , Princy Kumar , R Scott Turner , Margarita Bronshteyn , Nils Yang , Davidj Moore , Ronaldj Ellis , Matthew Dawson , Xiong Jiang , G William Rebeck , University Of California , Cognitive Neuroimaging Laboratory , Georgetown University Medical Center , National Institutes Of Health , Cognitive Neuroimaging , Fan Nils Yang , National Institutes , Medicine Health , Alzheimers Disease , ஜார்ஜ்டவுன் பல்கலைக்கழகம் , மாவட்டம் ஆஃப் கொலம்பியா , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ ,