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The Foreign Office confirmed the aircraft departed from the Wadi Saeedna airfield, near the capital of Khartoum, at 10pm local time on Saturday.
The Sudanese army has agreed to extend its truce with rebel paramilitary group RSF for another 72 hours, ahead of a last-gasp evacuation flight for Britons on Monday.
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The doctors have British visas with permission to live and work in the UK