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The PAncreatic Surgery Composite Endpoint PACE – Development and Validation of a Clinically Relevant Endpoint Requiring Lower Sample Sizes. - Vimarsana News

The PAncreatic Surgery Composite Endpoint PACE – Development and Validation of a Clinically Relevant Endpoint Requiring Lower Sample Sizes.

To provide a composite endpoint in pancreatic surgery.Single endpoints in prospective and randomized studies have become impractical due to their low frequency and the marginal benefit of new interventions.Data from prospective studies were used to develop (n=1273) and validate (n=544) a composite endpoint based on postoperative pancreatic fistula, post-pancreatectomy hemorrhage as well as reoperation and

Ascendis Pharma A/S Announces Phase 3 PaTHway Trial of TransCon™ PTH in Adults with Hypoparathyroidism Met Primary and All Key Secondary Endpoints - Vimarsana News

Ascendis Pharma A/S Announces Phase 3 PaTHway Trial of TransCon™ PTH in Adults with Hypoparathyroidism Met Primary and All Key Secondary Endpoints

–  For the primary composite endpoint, TransCon PTH demonstrated a response rate of 78.7% compared to 4.8% for control . –  TransCon PTH demonstrated statistically... | March 13, 2022

Ascendis Pharma A/S Announces Phase 3 PaTHway Trial of - Vimarsana News

Ascendis Pharma A/S Announces Phase 3 PaTHway Trial of

–  For the primary composite endpoint, TransCon PTH demonstrated a response rate of 78.7% compared to 4.8% for control (p-value <0.0001). –  TransCon...