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CWRU, University Hospitals are part of a $3 million grant project on lung cancer, immunotherapy


CWRU, University Hospitals are part of a $3 million grant project on lung cancer, immunotherapy
CWRU, University Hospitals are part of a $3 million grant project on lung cancer, immunotherapy
Anant Madabhushi
Researchers from Case Western Reserve University and University Hospitals are part of a $3 million National Cancer Institute grant to develop artificial intelligence tools to help predict which lung cancer patients would respond to immunotherapy.
The team also includes researchers from New York University on the five-year grant.
Clinical trials down the road will be our biggest test, but now we will be for the first time studying changes in the tissue-scan patterns of patients as they are being treated, and that will provide real-world context of our tools, said Anant Madabhushi, director of Case Western Reserve s Center for Computational Imaging and Personalized Diagnostics, said in a news release. Our AI tools have excelled in previous studies, bu ....

Anant Madabhushi , University Hospitals , Case Western Reserve Center , National Cancer Institute , York University , Case Western Reserve University , New York University , Case Western Reserve , Computational Imaging , Personalized Diagnostics , பல்கலைக்கழகம் மருத்துவமனைகள் , வழக்கு மேற்கு இருப்பு மையம் , தேசிய புற்றுநோய் நிறுவனம் , யார்க் பல்கலைக்கழகம் , வழக்கு மேற்கு இருப்பு பல்கலைக்கழகம் , புதியது யார்க் பல்கலைக்கழகம் , வழக்கு மேற்கு இருப்பு , கணக்கீட்டு இமேஜிங் , தனிப்பயனாக்கப்பட்டது பரிசோதனை ,

Case Western Reserve awarded $3 million National Cancer Institute grant to apply AI to immunotherapy


Date Time
Case Western Reserve awarded $3 million National Cancer Institute grant to apply AI to immunotherapy
Scientists, medical researchers at Case Western Reserve, NYU Langone Health and University Hospitals using machine-learning to predict response to immunotherapy
Medical researchers from Case Western Reserve University, New York University (NYU), and University Hospitals have been awarded a five-year, $3 million National Cancer Institute grant to develop and apply artificial intelligence (AI) tools for predicting which lung cancer patients will respond to immunotherapy.
A unique aspect of the Case Western Reserve-led study is that it will involve testing of their specific AI tools-for the first time during an ongoing clinical trial. ....

Stanton Gerson , Robert Gilkeson , Anant Madabhushi , Vamsidhar Velcheti , Pingfu Fu , Case Western Reserve School Of Medicine , Case Comprehensive Cancer Center , School Of Medicine , Langone Health , University Hospitals , National Cancer Institute , World Health Organization , Langone Perlmutter Cancer Center , Quantitative Health Sciences , Case Western Reserve Center , York University , Case Western Reserve University , University Hospitals Radiology Department Amit Gupta , Case Western Reserve , New York University , Case Western Reserve Led , Computational Imaging , Personalized Medicine , Perlmutter Cancer Center , World Health , Case Western Reserve School ,

Artificial Intelligence Identifies Lung Cancer Patients at Risk of Harm Caused by Immunotherapy


Artificial Intelligence Identifies Lung Cancer Patients at Risk of Harm Caused by Immunotherapy
February 9, 2021
In a subset of patients diagnosed with non-small cell lung cancer (NSCLC), immunotherapy paradoxically exacerbates tumor growth and significantly shortens survival. Currently there are no clinically validated biomarkers that can identify patients at risk of this paradoxical response called “hyperprogression.”
Using artificial intelligence (AI) analysis of simple tissue scans, researchers at Case Western University claim they have discovered biomarkers that could tell which lung cancer patients might get worse from immunotherapy.
In addition to those who would benefit from immunotherapy, and those who might not, researchers and oncologists can now identify a third category of patients called hyper-progressors who would be harmed by the same immunotherapy, says Pranjal Vaidya, a PhD student in biomedical engineering and researcher at the university’s ....

Pradnya Patil , Anant Madabhushi , Pranjal Vaidya , Donnell Institute Professor Of Biomedical Engineering , National Cancer Institute , Taussig Cancer Institute , Case Western University , Computational Imaging , Personalized Diagnostics , National Cancer , Donnell Institute Professor , Biomedical Engineering , Cleveland Clinic , பிரட்ஞய பாட்டீல் , பிரஞ்சள் வைத்யா , டோனெல் நிறுவனம் ப்ரொஃபெஸர் ஆஃப் உயிர் மருத்துவ பொறியியல் , தேசிய புற்றுநோய் நிறுவனம் , வழக்கு மேற்கு பல்கலைக்கழகம் , கணக்கீட்டு இமேஜிங் , தனிப்பயனாக்கப்பட்டது பரிசோதனை , தேசிய புற்றுநோய் , டோனெல் நிறுவனம் ப்ரொஃபெஸர் , உயிர் மருத்துவ பொறியியல் , கிளீவ்லேண்ட் சிகிச்சையகம் ,