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Safety and immunogenicity of aerosolised Ad5-nCoV, intramuscular Ad5-nCoV, or inactivated COVID-19 vaccine CoronaVac given as the second booster following three doses of CoronaVac: a multicentre, open-label, phase 4, randomised trial

A heterologous fourth dose (second booster) with either aerosolised Ad5-nCoV or intramuscular
Ad5-nCoV was safe and highly immunogenic in healthy adults who had been immunised
with three doses of CoronaVac. ....

Long Li , United States , Peng Wan , Xue Wang , Tao Zhu , J Clin Microbiol , Hai Tao Huang , Cansino Biologics , Technology Plan , National Natural Science Foundation Of China , Elsevier Ltd , Vazyme Medical Technology , Graphpad Prism , Jiangsu Province , Nat Med , N Specific Igg , Clin Microbiol , Specifict Cell , Power Analysis , Sample Size , National Natural Science Foundation , Jiangsu Provincial Science Fund , Distinguished Young Scholars , Jiangsu Provincial Key Project , Continuous Vapouring System ,

Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial

Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial
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Sinovac Coronavac , Cansino Biologics , National Natural Science Foundation Of China , Development Program , Jiangsu Provincial Key Research , Elsevier Ltd , National Natural Science Foundation , Continuous Vapouring System ,