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A heterologous fourth dose (second booster) with either aerosolised Ad5-nCoV or intramuscular Ad5-nCoV was safe and highly immunogenic in healthy adults who had been immunised with three doses of CoronaVac.
Researchers assess the respiratory mucosal immunity elicited by COVID-19 vaccination.
A new study aimed to demonstrate the reactivity of COVID-19 serum obtained from patients in Tatarstan, Russia with S and N peptides that were previously identified as immunogenic.
A new study revealed that the immune responses against SARS-CoV-2 and the clinical course of COVID-19 differs between children and adults.
Why does convalescent plasma therapy for severe COVID-19 show mixed success? Treatment modalities against the coronavirus disease 2019 (COVID-19) pandemic are limited in efficacy. This has led many centers to use convalescent plasma from recovered COVID-19 patients in the management of this condition. A surprising new preprint, released on the medRxiv* server, suggests that the beneficial effects of convalescent plasma (CP) in this disease stem not only from the presence of neutralizing antibodies, but also the immunomodulatory effects of this plasma that shapes the host immune response. Dis...