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The study investigates the relationship between antibody levels and behavioral factors in 176 adults vaccinated with Pfizer's BNT162b2, finding that higher levels of specific antibodies correlate with greater protection against symptomatic COVID-19. It also suggests that current commercial assays may need reformatting for better risk prediction.
Researchers evaluated distinct immune responses to mRNA and vector-based COVID-19 vaccines and natural SARS-CoV-2 infections.
Researchers reported that some monoclonal nAbs directed against distinct RBD epitopes nested inside the SARS-CoV-2 S could substitute ACE2 as a receptor and support fusion between viral and host cell membranes facilitating viral infectivity.
Researchers reported a class switch in SARS-CoV-2-specific antibodies due to repeated mRNA vaccinations.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits variable immunity responses among hosts based on symptom severity. Whether immunity in recovered individuals is effective for avoiding reinfection is poorly understood. Determination of immune memory status against SARS-CoV-2 helps identify reinfection risk and vaccine efficacy. Hence, after recovery from COVID-19, evaluation of protective effectiveness and durable immunity of prior disease could be significant. Recent reports described the dynamics of SARS-CoV-2 -specific humoral and cellular responses for more than six mon...