JABSOM researchers build on Human Genome Project advances | University of Hawaiʻi System News
JABSOM researchers are making advancements in biochemical reaction network analysis.
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JABSOM researchers are making advancements in biochemical reaction network analysis.
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UIC researchers are developing detectors for real-time identification of airborne viruses, promising a revolution in pandemic control.
Cell entry of most alphaherpesviruses is mediated by the binding of glycoprotein D (gD) to different cell surface receptors. Equine herpesvirus type 1 (EHV-1) and EHV-4 gDs interact with equine major histocompatibility complex I (MHC-I) to initiate entry into equine cells. We have characterized the gD-MHC-I interaction by solving the crystal structures of EHV-1 and EHV-4 gDs (gD1, gD4), performing protein-protein docking simulations, surface plasmon resonance (SPR) analysis, and biological assays. The structures of gD1 and gD4 revealed the existence of a common V-set immunoglobulin-like (IgV-l...
The Cold War mission to extract the world’s first complete ice core.