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When SARS-CoV-2, the virus that causes COVID-19, infects a human cell, it quickly begins to replicate by seizing the cell's existing metabolic machinery.
Warning signs for Alzheimer's disease (AD) can begin in the brain years before the first symptoms appear. Spotting these clues may allow for lifestyle changes that could possibly delay the disease's destruction of the brain.
U.S. opioid epidemic associated with increase in infective endocarditis and strokes The ongoing U.S. opioid epidemic may have led to an increase in the number of strokes due to more bacterial infections of the heart, or infective endocarditis, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2021. The virtual meeting is March 17-19, 2021 and is a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health. According to the most recent comprehensive data (January 2020) from the Ce...
Immune Cells in Brain Predict Response to Immunotherapy by Angela Mohan on March 8, 2021 at 6:18 PM Immune cells accessing cerebrospinal fluid recapitulate the characteristics of cells identified in brain metastasis, and could therefore constitute novel biomarkers of response to immune-based therapies, as per the study in Nature Communications, led by Joan Seoane, Director of Preclinical and Translational Research co-program at VHIO and ICREA Professor. Immune checkpoint inhibitors including anti-PD1, anti-PD-L1, and anti-CTLA4, have shown significant clinical benefits in...
E-Mail IMAGE: Joaquín Arribas, co-Program Director of Preclinical and Translational Research at VHIO, ICREA Professor, CIBERONC Investigator, Director of the Hospital del Mar Medical Research Institute (IMIM). view more Credit: VHIO Redirection of lymphocytes, via T-cell bispecific antibodies (TCBs) and chimeric antigen receptors (CARs), is already approved to treat some hematologic malignancies. In solid tumors these immune-based strategies continue to fail. Research led by Joaquín Arribas, co-Program Director of Preclinical and Translational Research at VHIO, has now show...